“This application-oriented work is the logical continuation of our successful endeavours over many years to understand the metabolism of CO2 reducing acetogenic bacteria. We can now start to steer their metabolism in such a way that they produce valuable substances and fuels which are interesting for mankind”, says Professor Volker Müller, professor at the Institute of Molecular Biosciences of Goethe University Frankfurt. He is coordinating this transnational project in the framework of the “Industrial Biotechnology” European Research Area Network (ERA-NET), within which the German research groups are financed by the Federal Ministry of Education and Research. This means that Goethe University Frankfurt now plays a pivotal role in the development of a next-generation technology.
The special group of acetogenic bacteria converts carbon dioxide (CO2) in a fermentation process which is independent of light and oxygen. The bacteria use hydrogen (H2) or carbon monoxide (CO) or a mix of both (synthesis gas) as a source of energy. However, the bacteria produce very little cellular energy in this metabolic process. This drastically limits the product range possible with gas fermentation, so that at present only acetic acid and ethanol can be manufactured on an industrial scale. That is why the collaborative European project has set itself the objective of genetically modifying suitable acetogenic bacteria in such a way that these energetic barriers can be overcome. Partners in the consortium are Goethe University Frankfurt as well as the universities in Ulm, Göttingen and La Coruna. ArcelorMittal, the largest steel manufacturer worldwide, is the industrial partner.
This microbial, CO2 based biotechnology could in future be an environmentally friendly alternative for the reprocessing of industrial waste gases rich in energy and carbon and reduce our dependency on crude oil. The microbial fixation and transformation of CO2 into raw materials produced biologically additionally makes it possible to reduce greenhouse gas emissions.